Development and validation of a high-performance liquid chromatography assay for voriconazole.

نویسندگان

  • Gennethel J Pennick
  • Martin Clark
  • Deanna A Sutton
  • Michael G Rinaldi
چکیده

An analytical method for the determination of voriconazole (UK-109,496; Pfizer) in plasma was developed and validated. The method utilizes solid-phase extraction technology and high-performance liquid chromatography. The lower limit of quantitation is 0.2 microg/ml, and the range of linearity tested was 0.2 to 10 microg/ml.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 47 7  شماره 

صفحات  -

تاریخ انتشار 2003